15^th International Congress on Autoimmunity August 16-17, 2021 London, UK

Conference Series take the pleasure to proudly present “International Conference on Autoimmunity” during August 16-17, 2021 as a Webinar with the theme “Modern approaches in autoimmunity”.

Autoimmunity disease is a condition arising from an abnormal immune response to a normal body part. There are at least 80 types of autoimmune diseases. Nearly any body part can be involved. Common symptoms include low grade fever and feeling tired. Often symptoms return and go. it's been calculable that reaction diseases area unit among the leading causes of death among ladies within the u. s. altogether age teams up to 65 years. As a result, health care agencies and market players, through various awareness programs, encourage routine reviews.

The global autoimmune disease therapeutics market was valued at $109,833 million in 2017, and is projected to reach $153,320 million by 2025, registering a CAGR of 4.2% from 2018 to 2025. An autoimmune diseaser causes the immune system to destroy its own body tissue. There are more than 80 different types of autoimmune disorders; however, lupus, multiple sclerosis, IBS, type 1 diabetes, rheumatoid arthritis, psoriasis, and others are the most common form of autoimmune disease. Different types of drugs such as anti-inflammatory, NSAIDs, interferons, immune suppressants, corticosteroids, and others, are approved for the treatment of autoimmune disease. It has been estimated that autoimmune diseases are among the leading causes of death among women in the United States in all age groups up to 65 years.

Autoimmune Disease Diagnosis market worldwide is projected to grow by US$2.4 Billion, guided by a compounded growth of 8.1%. While global megatrends sweeping through the market influence the primary direction of growth, regional markets are swayed by more granular locally unique business drivers. Representing the developed world, the United States will maintain a 6.9% growth momentum. Within Europe, which continues to remain an important element in the world economy, Germany will add over US$92.5 Million to the region's size and clout in the next 5 to 6 years. Over US$191.5 Million worth of projected demand in the region will come from other emerging Eastern European markets. In Japan, Consumables & Assay Kits can reach a market size of US$174.7 Million by the shut of the analysis amount. because the world's second largest economy and therefore the new game changer in international markets, China exhibits the potential to grow at eleven.7% over consequent number of years and add close to US$639.3 Million in terms of available chance for the choosing by aspiring businesses and their sharp leaders.

Asia-Pacific presents lucrative growth opportunities for the key players operating in the autoimmune disease therapeutics market owing to large population base, rise in purchasing power, surge in prevalence of autoimmune disease, and increase in demand for advanced autoimmune disease therapeutics. Growth in number of aging population, and increase in early detection of the disease with rise in healthcare expenditure fuel the growth of the autoimmune disease therapeutics market in this region.

Systemic lupus (SLE) may be a chronic autoimmune disorder with associate degree exaggerated risk of death compared to general population. Though previous studies showed improvement in survival of lupus, the long-run prognosis has not been elaborate in China. All pooled analyses were conducted each for random-effects model and fixed-effects model. Funnel plots and lasiocampid regression tests were applied to envision potential publication bias. No uniformity was tested by sensitivity analysis. We tend to known five studies for survival analysis comprising 4469 Chinese patients with lupus (380 discovered deaths). Thirty-six studies were appropriate for death-cause analysis with 2179 discovered deaths (derived from over twenty, Chinese patients with SLE). The overall pooled survival rates for SLE in China were 94% for 5-year survival rate and 89% for 10-year survival rate after disease onset from the year 1995 to 2013, which were similar with previous publications in Asia-Pacific area. The proportions of various causes of death showed infection (33.2%), urinary organ involvement (18.7%), lupus neurological disorder (13.8%), and upset (11.5%) because the high four causes.

Autoimmune diseases are a broad range of more than 80 related disorders that range from common to rare. They affect around 5% of people and are one of the most important chronic health problems in Australia and New Zealand. Common reaction diseases like rubor, arthritis and polygenic disease have an effect on quite 1 Chronicles of individuals. Lupus (SLE) affects but zero.1% of individuals and is a lot of common and severe in autochthonal Australians, Polynesians and folks descended from South East Asia.

 

 

 

 

 

Track 1: Autoimmune Diseases

Autoimmunity is the process of Immune Responses of an organism against its own tissues and cells. Any disease that results from such an unusual immune response is termed an autoimmune disease. Prominent examples include Diabetes Mellitus type 1, Systemic lupus Erythematous, Celiac disease, Sarcoidosis. Autoimmune diseases are very often treated with steroids.

Track 2: Infection and Autoimmunity

Virus infection may be a primary issue that has been concerned within the initiation of disease. Infection triggers a strong and frequently well-coordinated reaction that's important for infective agent clearance. However, in some instances, immune regulative mechanisms might falter, culminating within the breakdown of self-tolerance, leading to immune-mediated attack directed against each infective agent and self-antigens.

Track 3:  Autoimmunity in Women

The majority of people living with autoimmune complaints are women, frequently those who are of childbearing age. Autoimmune diseases, majority of these diseases are more common in women than in men a predictable 75% because this higher prevalence is partly attributable to the X chromosome, which has many genes relating to the immune system. Autoimmune diseases attack in women three times more than men. Some Autoimmune diseases have an even complex incidence in women.

Track 4: Autoimmune & Inflammatory Diseases

The immune system has the capacity to mount an immune response to virtually all molecules and/or cells. Although the capacity to respond to self-antigen is present in all of us, in most instances such responses result in tolerance, indicating that mechanisms must exist to prevent or subdue autoimmune responses. Moreover, auto-reactive T and B cells, as well as auto-antibodies, are found in people who do not have autoimmune diseases, demonstrating that immunological auto-reactivity alone is not sufficient for the development of the disease. The mechanisms currently thought to prevent/dampen autoimmune responses include inactivation or deletion of auto reactive B and T cells, active suppression by cells or cytokines, idiotype or anti-idiotype interactions, and the immunosuppressive adrenal hormones, the glucocorticoids.

Track 5: Thyroid Autoimmunity

Autoimmune thyroiditis is a chronic disease in which the body interprets the thyroid glands and its hormone products T3, T4 and TSH as threats, therefore producing special antibodies that target the thyroid’s cells, thereby destroying it. The symptoms may vary depending on the thyroid function, i.e. hyperthyroidism or hypothyroidism. Hyperthyroidism will cause sweating, speedy pulse rate, anxiety, tremors, fatigue, problem sleeping, unexpected weight loss, and sticking eyes. Hypothyroidism will cause weight gain, fatigue, dry skin, hair loss, intolerance to cold, and constipation. Autoimmune thyroiditis has a higher prevalence in societies that have a higher intake of iodine in their diet

Track 6:  Therapy of Autoimmune Liver Disease

Autoimmune hepatitis is a disease in which the body’s own immune system attacks the liver and causes it to become inflamed. The disease is chronic, meaning it lasts many years. If untreated, it can lead to cirrhosis and liver failure. There are two forms of this disease. Autoimmune hepatitis is characteristically responsive to corticosteroids, often used in combination with azathioprine to obtain a steroid-sparing effect. Therefore, autoimmune liver diseases are presently treated by suppression of the immune response.

Track 7: Immunotherapy

Immunotherapy is the treatment of disease by activating or suppressing the immune system. The use of immune system components or antigens to treat a disease or disorder is known as immunotherapy.  Immunotherapy is most commonly used to treat allergies, autoimmune disorders such as Crohn’s disease and rheumatoid arthritis, and certain cancers. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural killer cells (NK Cell), cytotoxic T lymphocytes (CTL), etc., work together to defend the body against cancer by targeting abnormal antigens expressed on the surface of tumor cells. Immunotherapies designed to elicit or amplify an immune response are classified as activation immunotherapies, while immunotherapies that reduce or suppress are classified as suppression immunotherapies.

Track 8: Molecular Immunology

Molecular immunology is a branch of immunology that concentrates to diagnose and analyze immune system and its processes at a molecular level. The immune system is the system that protects the living body from foreign entities, such as bacteria or other infectious agents in the body. The immune system has been divided into a more primitive innate immune system and, in vertebrates, an acquired or adaptive immune system. Molecular immunology deals with immune responses at cellular and molecular level. Molecular immunology has been evolved for better understanding of the sub-cellular immune responses for prevention and treatment of immune related disorders and immune deficient diseases.

Track 9: Cancer Immunology

Cancer immunology is division of biology which deals with understanding the role of the immune system in the development of cancer and string. The most well notable application in cancer immunology is cancer immunotherapy which taps the immune system as a treatment for cancer.

Track 10: Clinical Immunology

Immunology is the study of the immune system. The immune system is how all animals, including humans, protect themselves against diseases. The study of diseases caused by disorders of the immune system is clinical immunology. The disorders of the immune system fall into two broad categories:

· Immunodeficiency, in this immune system fails to provide an adequate response.

· Autoimmunity, in this immune system attacks its own host's body.

Track 11: Translational Immunology

Translational immunology is the process by which researchers use immunological discoveries to develop practical solutions for human problems. Examples include the development of vaccines against infectious diseases or the engineering of new types of drugs to treat inflammatory disorders.

Track 12: Types Of Immunology

Immunology charts, measures, and contextualizes the physiological functioning of the immune system in states of both health and diseases malfunctions of the immune system in immunological disorders such as autoimmune diseases hypersensitivities immune deficiency, and transplant rejection the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo. The study of the molecular and cellular elements that comprise the system as well as their operate and interaction is that the central science of medical specialty. Medical specialty has applications in varied disciplines of drugs notably within the fields of organ transplantation, oncology, medical specialty, virology, medical specialty, parasitology, psychiatry, and medical specialty. The body substance (antibody) response is outlined because the interaction between antibodies and antigens.

Track 13: Immune Diseases

The immune system has developed a variety of approaches to controlling viral and bacterial infection, which range from direct killing of pathogen to elaborating cytokines that inhibit replication.  Pathogens have countered by developing a variety of immune evasion mechanisms that inhibit cytokine function and prevent immune recognition of infected cells.  The human immune system typically produces both T cells and B cells that are capable of being reactive with self-antigens, but these self-reactive cells are usually either killed prior to becoming active within the immune system, placed into a state of, or removed from their role within the immune system by regulatory cells.

Track 14: Peptides and Autoimmune Diseases

Several self-molecules are known as target antigens in reaction diseases. Since lack or loss of tolerance to those molecules is one among the key events promoting pathology, researchers area unit exploring the chance that the administration of antigens or peptides might stimulate tolerogenic mechanisms and delay or forestall the complete phenotypical expression of reaction diseases.

Track 15: Prediction, Monitoring and Prevention

Forecast the end result of medical aid in clinical trials, or aid in developing improved treatments or preventative measures. All of those applications are applied to the response diseases. As a case in purpose, we've got through the years used biomarkers to predict status and therefore the longer-range outcome of thyroid pathology using, variety of various approaches